by Adam Washburn | Sep 21, 2016 | Scientific Publications
Abstract The analysis of disease-specific biomarker panels holds promise for the early detection of a range of diseases, including cancer. Blood-based biomarkers, in particular, are attractive targets for minimally-invasive disease diagnosis. Specifically, a panel of...
by Adam Washburn | Jan 8, 2012 | 2012 News, Publications, Scientific Publications
Abstract We have developed a broadly applicable biosensing platform based upon chip-integrated silicon photonic microcavities. Large arrays of microring resonators are robustly fabricated using standard semiconductor processing methods on silicon-on-insulator wafers....
by Adam Washburn | May 1, 2011 | Scientific Publications
Abstract High affinity capture agents against protein targets are essential components for immunoassays, regardless of specific analysis format. Here, we describe the use of DNA-encoded antibodies for rapidly screening the kinetic and equilibrium binding properties of...
by Adam Washburn | Oct 18, 2010 | Scientific Publications
Abstract By leveraging advances in semiconductor microfabrication technologies, chip-integrated optical biosensors are poised to make an impact as scalable and multiplexable bioanalytical measurement tools for lab-on-a-chip applications. In particular, waveguide-based...
by Adam Washburn | Dec 9, 2009 | Scientific Publications
Abstract Because of the inherent complexity of biochemical pathways commonly altered in disease states, it has become accepted that multiplexed analyses can provide a more informative biomolecular understanding of disease onset and progression. Importantly, compared...
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